Interesting Ingredient Comparison: Formula vs. Breastmilk

FORMULA INGREDIENTS

Water Carbohydrates
Lactose
Corn maltodextrin Protein
Partially hydrolyzed reduced minerals whey protein concentrate (from cow’s milk) Fats
Palm olein
Soybean oil
Coconut oil
High oleic safflower oil (or sunflower oil) M. alpina oil (Fungal DHA)
C.cohnii oil (Algal ARA) Minerals
Potassium citrate Potassium phosphate Calcium chloride Tricalcium phosphate Sodium citrate Magnesium chloride Ferrous sulphate
Zinc sulphate Sodium chloride Copper sulphate Potassium iodide Manganese sulphate Sodium selenate
Vitamins
Sodium ascorbate Inositol
Choline bitartrate Alpha-Tocopheryl acetate Niacinamide
Calcium pantothenate Riboflavin
Vitamin A acetate Pyridoxine hydrochloride Thiamine mononitrate Folic acid
Phylloquinone
Biotin
Vitamin D3
Vitamin B12
Enzyme Trypsin
Amino acid Taurine
L-Carnitine (a combination of two different amino acids) Nucleotides
Cytidine 5-monophosphate
Disodium uridine 5-monophosphate Adenosine 5-monophosphate Disodium guanosine 5-monophosphate
Soy Lecithin


HUMAN MILK INGREDIENTS

Water
Carbohydrates (energy source)
Lactose
Oligosaccharides (see below) Carboxylic acid
Alpha hydroxy acid Lactic acid
Proteins (building muscles and bones) Whey protein
Alpha-lactalbumin
HAMLET (Human Alpha-lactalbumin Made Lethal to Tumour cells)
Lactoferrin
Many antimicrobial factors (see below) Casein
Serum albumin Non-protein nitrogens
Creatine
Creatinine
Urea
Uric acid
Peptides (see below)
Amino Acids (the building blocks of proteins)
Alanine Arginine Aspartate Clycine Cystine Glutamate Histidine Isoleucine Leucine Lycine Methionine Phenylalanine Proline
Serine
Taurine
Theronine
Tryptophan
Tyrosine
Valine
Carnitine (amino acid compound necessary to make use of fatty acids as an energy source)
Nucleotides (chemical compounds that are the structural units of RNA and DNA) 5’-Adenosine monophosphate (5”-AMP)
3’:5’-Cyclic adenosine monophosphate (3’:5’-cyclic AMP)
5’-Cytidine monophosphate (5’-CMP)
Cytidine diphosphate choline (CDP choline) Guanosine diphosphate (UDP)
Guanosine diphosphate - mannose
3’- Uridine monophosphate (3’-UMP) 5’-Uridine monophosphate (5’-UMP) Uridine diphosphate (UDP)
Uridine diphosphate hexose (UDPH)
Uridine diphosphate-N-acetyl-hexosamine (UDPAH) Uridine diphosphoglucuronic acid (UDPGA)
Several more novel nucleotides of the UDP type
Fats Triglycerides
Long-chain polyunsaturated fatty acids
Docosahexaenoic acid (DHA) (important for brain development) Arachidonic acid (AHA) (important for brain development) Linoleic acid
Alpha-linolenic acid (ALA)
Eicosapentaenoic acid (EPA)
Conjugated linoleic acid (Rumenic acid)
Free Fatty Acids Monounsaturated fatty acids
Oleic acid Palmitoleic acid Heptadecenoic acid
Saturated fatty acids Stearic
Palmitic acid Lauric acid Myristic acid
Phospholipids
Phosphatidylcholine Phosphatidylethanolamine Phosphatidylinositol Lysophosphatidylcholine Lysophosphatidylethanolamine Plasmalogens
Sphingolipids Sphingomyelin
Gangliosides GM1 GM2 GM3
Glucosylceramide Glycosphingolipids Galactosylceramide Lactosylceramide Globotriaosylceramide (GB3) Globoside (GB4)
Sterols Squalene
Lanosterol Dimethylsterol Methosterol
Lathosterol Desmosterol Triacylglycerol Cholesterol 7-dehydrocholesterol Stigma-and campesterol 7-ketocholesterol Sitosterol
ß-lathosterol
Vitamin D metabolites Steroid hormones
Vitamins Vitamin A
Beta carotene Vitamin B6
Vitamin B8 (Inositol) Vitamin B12 Vitamin C
Vitamin D Vitamin E
a-Tocopherol Vitamin K
Thiamine Riboflavin Niacin
Folic acid Pantothenic acid Biotin
Minerals Calcium
Sodium Potassium Iron
Zinc Chloride Phosphorus Magnesium Copper Manganese Iodine Selenium Choline Sulpher Chromium Cobalt Fluorine Nickel
Metal
Molybdenum (essential element in many enzymes)
Growth Factors (aid in the maturation of the intestinal lining) Cytokines
interleukin-1ß (IL-1ß) IL-2
IL-4
IL-6
IL-8
IL-10
Granulocyte-colony stimulating factor (G-CSF) Macrophage-colony stimulating factor (M-CSF)
Platelet derived growth factors (PDGF)
Vascular endothelial growth factor (VEGF)
Hepatocyte growth factor -a (HGF-a)
HGF-ß
Tumor necrosis factor-a
Interferon-?
Epithelial growth factor (EGF)
Transforming growth factor-a (TGF-a)
TGF ß1
TGF-ß2
Insulin-like growth factor-I (IGF-I) (also known as somatomedin C) Insulin-like growth factor- II
Nerve growth factor (NGF)
Erythropoietin
Peptides (combinations of amino acids) HMGF I (Human growth factor) HMGF II
HMGF III
Cholecystokinin (CCK)
ß-endorphins
Parathyroid hormone (PTH)
Parathyroid hormone-related peptide (PTHrP) ß-defensin-1
Calcitonin
Gastrin
Motilin
Bombesin (gastric releasing peptide, also known as neuromedin B) Neurotensin
Somatostatin
Hormones (chemical messengers that carry signals from one cell, or group of cells, to another
via the blood) Cortisol
Triiodothyronine (T3)
Thyroxine (T4)
Thyroid stimulating hormone (TSH) (also known as thyrotropin) Thyroid releasing hormone (TRH)
Prolactin
Oxytocin
Insulin
Corticosterone
Thrombopoietin
Gonadotropin-releasing hormone (GnRH)
GRH
Leptin (aids in regulation of food intake)
Ghrelin (aids in regulation of food intake)
Adiponectin
Feedback inhibitor of lactation (FIL)
Eicosanoids
Prostaglandins (enzymatically derived from fatty acids) PG-E1
PG-E2
PG-F2 Leukotrienes
Thromboxanes
Prostacyclins
Enzymes (catalysts that support chemical reactions in the body)
Amylase Arysulfatase Catalase Histaminase
Lipase
Lysozyme PAF-acetylhydrolase Phosphatase Xanthine oxidase
Antiproteases (thought to bind themselves to macromolecules such as enzymes and as a result prevent allergic and anaphylactic reactions)
a-1-antitrypsin
a-1-antichymotrypsin
Antimicrobial factors (are used by the immune system to identify and neutralize foreign objects, such as bacteria and viruses.
Leukocytes (white blood cells) Phagocytes
Basophils Neutrophils Eoisinophils
Macrophages Lymphocytes
B lymphocytes (also known as B cells)
T lymphocytes (also known as C cells)
sIgA (Secretory immunoglobulin A) (the most important antiinfective factor) IgA2
IgG
IgD
IgM
IgE
Complement C1
Complement C2
Complement C3
Complement C4
Complement C5
Complement C6
Complement C7
Complement C8
Complement C9
Glycoproteins
Mucins (attaches to bacteria and viruses to prevent them from clinging to mucousal tissues)
Lactadherin
Alpha-lactoglobulin
Alpha-2 macroglobulin
Lewis antigens
Ribonuclease
Haemagglutinin inhibitors
Bifidus Factor (increases growth of Lactobacillus bifidus - which is a
good bacteria)
Lactoferrin (binds to iron which prevents harmful bacteria from using the
iron to grow)
Lactoperoxidase
B12 binding protein (deprives microorganisms of vitamin B12)
Fibronectin (makes phagocytes more aggressive, minimizes inflammation, and repairs
damage caused by inflammation) Oligosaccharides (more than 200 different kinds!)

SOURCE: These two lists were developed by Cecily Heslett, Sherri Hedberg and Haley Rumble as a student project for the Breastfeeding Course for Health Care Providers at Douglas College in New Westminster, BC, Canada in 2007. You can view the full pdf poster students created here. Note that we are still discovering new 'ingredients' in human milk each year. The science of lactation is relatively new and there is still a significant amount that we do not understand, and have not yet solved. It is very possible that the ingredient list for human milk is three times this length, with special factors we may not unfold for years to come.

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

I need a degree in advanced chemistry to get through that!

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Wow, pretty cool! It is amazing what our bodies can provide for our LO's.

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Wow, thanks for sharing, that is very interesting. I knew BM had lots of benefits but that far exceeds what I had thought. Still not to say that formula is harmful and that many many babies thrive on it.

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Tryptophan - thats interesting because I read once that if you pump, not to feed your baby the night milk during the day. A woman's milk in the evening will make a baby more sleepy. It must have more trptophan.l

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

I'm a BFing (pumping) mom, and I have no idea what any of these mean

I would love to know what the benefit from all of these are, not just a list of big words.

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

So amazing! I recently read that as baby starts to wean & gets less breast milk during the day, that the milk becomes stronger in antibodies/nutricious value to make up for less being drunk. So cool how your body knows!!

I wish my ped would read this...he told me the only thing in breastmilk that's not in formula is my antibodies!

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Meh *shrug*
Makes no diff to me

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Wow - that's amazing!

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Interesting. Ironically though if I saw something on the shelf with that many ingredients I'd probably steer clear of it!

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

This is amazing. Thanks for posting. I nursed #1 and will def nurse and pump longer for #2 AND use formula as well.

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Truly amazing how our bodies provide for our little ones!

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Posted by Disneygirl

Interesting. Ironically though if I saw something on the shelf with that many ingredients I'd probably steer clear of it!

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Once again, I bow to the power of human body, boobies especially so!

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

this makes me feel better as im locked in a back room of a school pumping.
thanks

a reminder that it is all worth it

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Oh my, that's amazing!

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Posted by Champ

this makes me feel better as im locked in a back room of a school pumping.
thanks

a reminder that it is all worth it

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Posted by WhatNow

Once again, I bow to the power of human body, boobies especially so!

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

The other side is that there are so many more nutrients in BM that haven't been discovered...also nutrients change throughout the day and from diet. For example, DHA, Vit D, and BM has been shown to be deficient in crucial nutrients if a mom does not have a healthy diet.

Formula has come a long way, but will never be BM - good or bad..LOL!

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk

Posted by Katareen

Posted by WhatNow

Once again, I bow to the power of human body, boobies especially so!

It's not really a human thing--more like a mammal thing

Re: Interesting Ingredient Comparison: Formula vs. Breastmilk