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BFN on 2nd Round of IVF no FE ...PGD? SA?

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JulieLO
LIF Adolescent

Member since 12/11

669 total posts

Name:

BFN on 2nd Round of IVF no FE ...PGD? SA?

So we just got news that our 2nd round of IVF didnt work. Out of 21 follies, 14 retrieved, 8 mature, 7 fertilized ONLY ONE was a blast and didnt take.

Going for blood and sono tomorrow and starting 3rd round of IVF...

Anyone do a DNA Sperm analysis.karyotype and/or PGD? I think that is next for us...any advice would help...thanks!

Posted 4/30/12 1:17 PM
 
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Kris828
Hopeful...

Member since 9/10

1322 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

Dh had a SA and they had found DNA fragmentation. Now we're dealing with some other issues. Our dr told him some "options" that could help.

Posted 4/30/12 1:53 PM
 

moonmist09
Thank you, St. Gerard!

Member since 2/11

5043 total posts

Name:
Antonella

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

no advise, but sending lots of Chat Icon Chat Icon Chat Icon Chat Icon Chat Icon Chat Icon your way

Posted 4/30/12 2:28 PM
 

NYCGirl80
I love my kiddies!

Member since 5/11

10413 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

I'm so sorry! Chat Icon

Do you mind telling us what your/your husband's diagnosis is? How did your embryos look on day 3?

Posted 4/30/12 2:29 PM
 

FlowerWife
Positive Vibrations...

Member since 1/08

8423 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

we did dna defragmentation prior to IVF because my DH had a slight morphology issue. turned out he just needed to take antioxidants.

Posted 4/30/12 2:36 PM
 

JulieLO
LIF Adolescent

Member since 12/11

669 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

We have "undiagnosed infertility"
His SA came back perfect...
Our story in a nutshell...
tried 1 year on own got pregnant MC 4months
9 IUI's
1 IVF- 22 Follies, 16 Eggs, 8IVF/8ICSI
10 embryo's, 2 blasts, and I have my MIRACLE THOMAS...
2nd IVF- 21 F, 8 mature egs, 7 fertilized ICSI
NONE

After discussion with the dr. if my genetics were comprimised
A. the eggs wouldn't be mature
B. would have never fertilized
C. never made it to blast 5DT

we do 5 day transfers...
we go tomorrow...PGD is SO EXPENSIVE and on top of the IVF portion that is NOT COVERED (MEDS & Retrieval) by insurance--Im going for broke :)

Posted 4/30/12 3:25 PM
 

JulieLO
LIF Adolescent

Member since 12/11

669 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

Anyone do 3 IVF cycles? Reasons? Id like to go tomorrow with some questions and pick her brain...Chat Icon

Posted 4/30/12 3:28 PM
 

PitterPatter11
Baby Boy is Here!

Member since 5/11

7610 total posts

Name:
Momma <3

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

No advice, just wanted to send Chat Icon Chat Icon Chat Icon Chat Icon Chat Icon

Posted 4/30/12 4:30 PM
 

NYCGirl80
I love my kiddies!

Member since 5/11

10413 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

It sounds like you did 1 IVF and it worked. And then your 2nd failed. Not 2 failed IVFs, right? Chat Icon

Could just be a blip.

Posted 4/30/12 5:15 PM
 

CindySN23
Stop, Think & Breathe...

Member since 8/11

3550 total posts

Name:
Cindy

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

I am so sorry Chat Icon

Posted 4/30/12 6:27 PM
 

JulieLO
LIF Adolescent

Member since 12/11

669 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

Yes, Round 1 IVF worked...round 2 didnt...
and the 9 IUI's before that didnt work either...Chat Icon

Could be a blip but the RE seems to think something is wrong since out of all the eggs I make and all the ones that fertilize none lived to freeze...

Posted 4/30/12 8:08 PM
 

TyReseGreen
Lil Prince is here

Member since 8/11

6338 total posts

Name:
Theresa

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

Secondary Infertility due to tubal ligation

First Round of IVF: Cancelled: prematurely ovulated

Second Round of IVF:
17 eggs retrieved, 14 fertilized, 2 day 3embies tranferred; let 7 go to day 5 blasts not all survived; rest frozen BFN

FET #1 BFN 2 day 5 blast
FET #2 BFN 2 day 3 embies
FET#3 Beta is tomorrow but at 8dp3dt POAS and got a BFN;

Posted 5/1/12 6:11 AM
 

1peanut
LIF Infant

Member since 2/10

87 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

I wouldn't jump the gun on doing PGD. Even with doing it, there is no guarantee it will work. If you have no known issues genetically, I'd give it another shot.

We have to do PGD due to genetic disorder, and we had three failed rounds.

IVF#1 -- 7 eggs, all mature, nothing fertilized
IVF#2 -- 10 eggs, 8 mature, 6 biopsied, one normal chromosomally and disorder free, chemical
IVF#3 -- 10 eggs, 9 mature, 5 fertilized, one normal, BFN.

DD#1 is a PGD/IVF baby and will be 3 in august.

Keep your chin up and look into natural methods to help (acupuncture, herbs) before going down that road.

Posted 5/1/12 8:08 AM
 

JulieLO
LIF Adolescent

Member since 12/11

669 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

I understand ---

We are getting the DNA Frag Test done ASAP...going to dr. this morning to figure out next steps. THey mentioned PGD becuase with our results (or lack thereof) it seems to be genetic.

Thanks Ladies!!! Nice to know Im not the only one Chat Icon

Posted 5/1/12 8:41 AM
 

JulieLO
LIF Adolescent

Member since 12/11

669 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

THERESA---Chat Icon Chat Icon Chat Icon Chat Icon

8dp3dt is still early for a BFP...keep the faith...My GF was 12dp5dt and got a BFN and her beta came up BFP...Chat Icon Ill include you in my prayers...

Posted 5/1/12 8:45 AM
 

01ellie
LIF Adult

Member since 9/10

2245 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

my first IVF i had 11 eggs retrieved, about 8 or 9 fertilized, 2 made it to blast which we transferred but the others didnt. I had a bfn that cycle, we were told it could be embryo quality issues or egg issues. i was so depressed just thinking about the price of pgd. Then the RE told me that even if i did the sperm fragmentation test it wouldnt affect how we did the next cycle. so i couldnt understand why would we want to do it?

anyways....my 2nd IVF we decided to do the ER 2 days earlier than before and then we did a 3 day transfer instead of 5 day. and that cycle worked!

try not to get too stressed maybe it can be something as simple as how long you were on stims or doing a 3 day vs a 5 day?

Posted 5/1/12 9:36 AM
 

NYCGirl80
I love my kiddies!

Member since 5/11

10413 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?


try not to get too stressed maybe it can be something as simple as how long you were on stims or doing a 3 day vs a 5 day?



ITA. One failed IVF cycle could really be a random piece of bad luck. Remember, only 50% of IVF cycles work, so you're still in the normal range. See what your dr recommends about your next protocol.

Posted 5/1/12 11:10 AM
 

JulieLO
LIF Adolescent

Member since 12/11

669 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

The DNA Frangmentation test will just give us a piece of mind as to weather the sperm genetics are comprimised. It will not change our cycle plan...

We decided against doing PGD only because 1. they can only do it on Day5 embryos
2. depending on how many I have (and based on past 2 cycles I didnt have but 2 full balsts) it wouldn't be worth the $6000 on that few embryos.
3. even if we did #2, the FET would be less likely to take then if we were to transfer D5 on a fresh cycle.

I understand IVF is 50/50.

Reviewing our past cycle it seems as though I made 2 sets of eggs...based on follie size and the amount retrieved vs. mature.

They put me on BC for 10 days and we will get the DNA SA results next friday. I will then start either cetrocide/ganarellix/leupron
for 10 days-- up my dose of follistim to 225-250 and stim for 11-12 days to try and give me more/mature eggs...looking for follies >18.

We will still do ICSI on all mature eggs and stay with a D5T.
Chat Icon Im excited to start again and hopefully be blessed with another baby. It happened once so I know it can happen again, just in due time...

One would think that after 5 years of infertility and soooooo many failed attempts weather trying on your own (1 year), 9 IUI's,2 IVF's , and a MC 16wks. that you would get used to the dissapointments...it doesnt seem to get any easier... but for me now that I do have a baby it doesnt last as long...just buckling up my boot straps and starting all over again...

Chat Icon

Posted 5/1/12 8:02 PM
 

JulieLO
LIF Adolescent

Member since 12/11

669 total posts

Name:

Re: BFN on 2nd Round of IVF no FE ...PGD? SA?

FlowerWife---what type of antioxidents did he take? Ill go out tomorrow and buy GNC Chat Icon

Posted 5/1/12 8:05 PM
 
 

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