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mommy-of-2-angels
It's all about Sophia
Member since 9/07 1731 total posts
Name:
Laurie
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MTHFR
does anymore have any info on this??? I have read a little about it and I don't really understand what I am reading I kinda need lamens term if anyone has any info thanks
Message edited 9/17/2007 9:04:39 AM.
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Posted 9/17/07 8:56 AM  |
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LaurenExp
Waiting patiently for baby sis
Member since 8/06 11613 total posts
Name:
L-Diddy EDD 11/11/11 :)
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Re: MTHFR
Great...now you just made me research it a little more and now I scared the crap out of myself. I have the homozyogous form. I just take folic acid supplements. The doctor told me my body doesn't process folic acid properly and could be a factor for infertility. Here is what I found on wiki (PS - I am NOT telling DH about the schizophrenia part, that's all he needs, more ammunition  ):
There is a common DNA sequence variant (polymorphism) in MTHFR at basepair 677 (a change from a C to a T) that results in a thermolabile enzyme with decreased enzymatic activity. 10% of the North American population are homozygous for this polymorphism (the incidence is higher in Mediterranean countries and lower in African-Americans). 677TT individuals are predisposed to mild hyperhomocysteinemia (high blood homocysteine levels), because they have less MTHFR available to produce 5-methyltetrahydrofolate (which is used to decrease homocysteine). Low dietary intake of the vitamin folic acid can also cause mild hyperhomocysteinemia. This polymorphism and mild hyperhomocysteinemia are associated with neural tube defects in offspring, arterial and venous thrombosis and cardiovascular disease. Interestingly, 677TT individuals are at a decreased risk for certain leukemias and colon cancer, but only when their dietary intake of folate is high. The MTHFR gene could be one of the factors of overall schizophrenia risk.[1] Schizophrenic patients having the risk allele (T\T) show more deficiencies in executive function tasks.[2]
Message edited 9/17/2007 9:11:09 AM.
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| Posted 9/17/07 9:10 AM |
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imyself
Member since 10/06 2938 total posts
Name:
me
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Re: MTHFR
you have fm 
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| Posted 9/17/07 4:02 PM |
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