PGD.

Our RE recommended that we do this on our next iivf round. At first I was like no way because of the cost, but I have been starting to reconsider. Will anyone be willing to share their thoughts on this?

We are unexplained and all of our generic testing has commie back normal. DH still has to do the sperm fragmentation test though....

Re: PGD.

My RE was recommending it also. How much does it usually cost? I heard it was pretty $$ but worth it. After my wedding, we are beginning the IVF process.

Re: PGD.

We did PGD. In addition to IVF costs, it was around an additional 5k.

Message edited 8/8/2013 10:56:56 PM.

PGD.

We did it. It is in addition to IVF costs, not covered by insurance but gave me a healthy DD! Also, the new thing with PGD is doing a sampling at 4-5 days and coverting to frozen. You get more info with 4-6 day old embies. BEST OF LUCK

Re: PGD.

What does PGD stand for? What is the benefit?

PGD.

Nothing important to add but good luck ad sending you good thighs and lots of stickies. Xo

Re: PGD.

We were considering it. Our RE really wanted us to get it done but our MFM said it wasn't necessary. It really depends on what they are doing the PGD testing for. You can check for a single gene mutation or an array of possible genetic issues.

We were looking for a specific mutation, and the MFM said that checking for that single mutation could mean that other genetic issues would go overlooked. In addition, our concern was for a condition that only has a 3% chance of being severe enough to effect our child's life (not terribly). And that was IF and only IF my DH was a carrier (results 2x were inconclusive).

We only had 4 eggs fertilize so to take the chance to lose some healthy embryos we just couldn't justify.

For those who are having the testing done to rule out life altering diseases or have A large number of embroys to test, iI think it's great.

Re: PGD.

PGD.

We have had several unexplained losses and two losses due to trisomy. Our RE recommend that we do this next fresh cycle. We have a frozen one now but they can thaw and test it with the next batch.

Re: PGD.

We just did PGD. We had 3 losses last year, one of which was at 20 weeks due to a triploid (extra set of chromosomes). Our RE felt it was necessary. We paid about 5K out of pocket for it.

I don't regret doing it; we ended up surpassing the normal 50% rate of normal: abnormal embryos by getting 3 out of 4 normal that we tested. Our first FET was negative, but we are going for the next one in Sept. One thing I learned was that it's not a guarantee that it will stick, even if it's genetically "normal".

The one piece of info I wish I'd known ahead of time, just to mentally prepare, is that I had to bank 3 cycles just to get to the point of doing PGD. You pay the 5K for up to 8 embryos, and since appx 50% come back normal, it's not worth testing 1 or 2. We had to wait out each cycle to day 5 to see how many fertilized embryos survived, freeze it, and go onto another fresh cycle. It was frustrating, taking all the injections each month and not transferring. I had no idea it would take 3-4 months to transfer, which was hard. Still, I knew that due to my past losses, this was the best move for us.

Please feel free to FM me with any other questions.

Re: PGD.

I'd say PPs' estimates of 5k are about right. Mine will be 6k because it's CCRM and they charge more for freaking everything. The type of biopsy is important. Some places are still doing a day-3 biopsy, which is unreliable and risks damaging an otherwise good embryo. Day-5 biopsies are more reliable because they sample a few cells (instead of just one) from the trophectoderm (outer part that becomes placenta, not baby) and don't pose the same risks.

Also, PGD only tests a handful of chromosomes that are common places for errors, whereas PGS tests them to make sure all the pairs are there. It's important to know which of these types of biopsies/screenings they're actually doing.

GL!