What exactly is lupron for?

I'm just wondering because the doctor told me I won't be taking it...and I was wondering why.
Of course, didn't think to ask why right then...but I know you guys will have the answer!!

Re: What exactly is lupron for?

Lupron supresses the ovaries so that ovulation cannot occur on its own.

Lupron (leuprolide acetate)

Lupron is given in IVF cycles according to patient specific protocols usually the "luteal Lupron" or "flare" protocols. Initially, Lupron stimulates the pituitary to release FSH (flare effect) within 7-10 days, however, Lupron will inhibit the production of gonadotropin releasing hormone. Since GnRH is required to cause the pituitary to produce FSH and LH, Lupron essentially "shuts down" the bodies reproductive hormone system.

While down regulated, IVF patients receive externally administered FSH (Gonal-F, Follistim) to cause the recruitment and development of follicles. Dosages of FSH are adjusted based upon each patient's response and it is continued until the follicles are mature.

Ovulation cannot occur naturally while on Lupron because LH, which triggers ovulation, is suppressed. This prevents a premature surge of LH before the retrieval, which could cause loss of the cycle. Once the eggs are mature, an injection of hCG or LH is given to stimulate ovulation and retrieval is scheduled 35 hours later.

When a patient is on the "luteal Lupron" protocol she usually starts Lupron 7 days prior to her next menstrual cycle. Dosages are adjusted based upon each patient's individual response. The "flare protocol" is usually used in poor responders. When Lupron is first administered there is a characteristic initial increase in FSH for several days followed by suppression. Lupron is administered on day 2 on the menstrual cycle and FSH is added to take advantage of this initial surge in FSH.

Re: What exactly is lupron for?

I don't know an exact answer to your question- I only know it suppresses but I can say that on my last IVF cycle the RE didnt have me do Lupron, and this cycle we are- so I guess it just depends on what type of protocol they want to try -to see what works best for you...In my case, I had poor fertlization the 1st time and the doctor thought the Lupron might give us some better quality ...Good Luck !

Re: What exactly is lupron for?

Thanks!!