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Blood pressure medicine...

Posted By Message

SerraMaMa
LIF Adult

Member since 10/07

982 total posts

Name:
Lauren

Blood pressure medicine...

Anyone have any info about being put on it during pregnancy?

Posted 12/8/08 6:41 PM
 
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newtothis
LIF Infant

Member since 11/08

150 total posts

Name:
l

Re: Blood pressure medicine...

I know there are certain classes of BP meds that you cannot take- but i believe there are some that are safe.

Posted 12/8/08 7:14 PM
 

asecretmommytobe09
My little pumpkin is here!!!!

Member since 10/08

3369 total posts

Name:
Katie

Re: Blood pressure medicine...

Posted by SerraMaMa

Anyone have any info about being put on it during pregnancy?



i take BP medicine. Labatilol, its a beta blocker. Beta Blockers are safe to take during pregnancy, they are Class B drugs. I think Hydralizine is another one.

Posted 12/8/08 7:25 PM
 

SweetTooth
I'm a tired mommy!

Member since 12/05

20105 total posts

Name:
Lauren

Re: Blood pressure medicine...

I'm on procardia now to stop contractions, but its first purpose is as a blood pressure med.

Posted 12/9/08 2:53 PM
 

pharmcat2000
Mom of 2 + 1

Member since 10/05

7395 total posts

Name:
Catherine

Re: Blood pressure medicine...

Posted by asecretmommytobe09

Posted by SerraMaMa

Anyone have any info about being put on it during pregnancy?



i take BP medicine. Labatilol, its a beta blocker. Beta Blockers are safe to take during pregnancy, they are Class B drugs. I think Hydralizine is another one.



I don't usually like to correct people, but beta blockers aren't class B drugs. For the most part, they are class C during the first trimester and class D during the second and third trimesters. Speaking specifically of labetolol, the manufacturer rates it as a C but other medical experts rate it as a D in the 2nd and 3rd trimester.

Aldomet (methyldopa) is the only drug for high BP that is rated category B for use during pregnancy.

ETA: Definition of categories of drugs during pregnancy

A: Controlled studies in women fail to demonstrate a risk to the fetus in the first trimester (and there is no evidence of a risk in later trimesters), and the possibility of fetal harm appears remote.

B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women, or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the first trimester (and there is no evidence of a risk in later trimesters).

C: Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus.

D: There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).

X: Studies in animals or human beings have demonstrated fetal abnormalities, or there is evidence of fetal risk based on human experience or both, and the risk of the use of the drug in pregnant women clearly outweighs any possible benefit. The drug is contraindicated in women who are or may become pregnant.

Message edited 12/9/2008 3:23:39 PM.

Posted 12/9/08 3:17 PM
 

stickydust
Now a mommy of 2!!!

Member since 4/06

3164 total posts

Name:

Re: Blood pressure medicine...

Posted by pharmcat2000

Posted by asecretmommytobe09

Posted by SerraMaMa

Anyone have any info about being put on it during pregnancy?



i take BP medicine. Labatilol, its a beta blocker. Beta Blockers are safe to take during pregnancy, they are Class B drugs. I think Hydralizine is another one.



I don't usually like to correct people, but beta blockers aren't class B drugs. For the most part, they are class C during the first trimester and class D during the second and third trimesters. Speaking specifically of labetolol, the manufacturer rates it as a C but other medical experts rate it as a D in the 2nd and 3rd trimester.

Aldomet (methyldopa) is the only drug for high BP that is rated category B for use during pregnancy.

ETA: Definition of categories of drugs during pregnancy

A: Controlled studies in women fail to demonstrate a risk to the fetus in the first trimester (and there is no evidence of a risk in later trimesters), and the possibility of fetal harm appears remote.

B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women, or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the first trimester (and there is no evidence of a risk in later trimesters).

C: Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus.

D: There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).

X: Studies in animals or human beings have demonstrated fetal abnormalities, or there is evidence of fetal risk based on human experience or both, and the risk of the use of the drug in pregnant women clearly outweighs any possible benefit. The drug is contraindicated in women who are or may become pregnant.



While you are correct about the actual class of the drugs many beta blockers have been used successfully in pregnancy for decades. There have been many studies done on the use of propanolol during pregnancy. In addition, you would probably be hard pressed to find an OB who would feel uncomfortable prescribing medications such as propanolol, metropolol and procardia during pregnancy.

It is also a matter of weighing the risks of not taking the medication with the risks involved in taking the medication. Often times you do not have much choice and anecdotal evidence demonstrates little to no risk. I was on propanolol while pregnant with DD and delivered a healthy girl with no IUGR at all.

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Message edited 12/9/2008 5:28:25 PM.

Posted 12/9/08 5:27 PM
 

pharmcat2000
Mom of 2 + 1

Member since 10/05

7395 total posts

Name:
Catherine

Re: Blood pressure medicine...

Posted by stickydust

Posted by pharmcat2000

Posted by asecretmommytobe09

Posted by SerraMaMa

Anyone have any info about being put on it during pregnancy?



i take BP medicine. Labatilol, its a beta blocker. Beta Blockers are safe to take during pregnancy, they are Class B drugs. I think Hydralizine is another one.



I don't usually like to correct people, but beta blockers aren't class B drugs. For the most part, they are class C during the first trimester and class D during the second and third trimesters. Speaking specifically of labetolol, the manufacturer rates it as a C but other medical experts rate it as a D in the 2nd and 3rd trimester.

Aldomet (methyldopa) is the only drug for high BP that is rated category B for use during pregnancy.

ETA: Definition of categories of drugs during pregnancy

A: Controlled studies in women fail to demonstrate a risk to the fetus in the first trimester (and there is no evidence of a risk in later trimesters), and the possibility of fetal harm appears remote.

B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women, or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the first trimester (and there is no evidence of a risk in later trimesters).

C: Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus.

D: There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective).

X: Studies in animals or human beings have demonstrated fetal abnormalities, or there is evidence of fetal risk based on human experience or both, and the risk of the use of the drug in pregnant women clearly outweighs any possible benefit. The drug is contraindicated in women who are or may become pregnant.



While you are correct about the actual class of the drugs many beta blockers have been used successfully in pregnancy for decades. There have been many studies done on the use of propanolol during pregnancy. In addition, you would probably be hard pressed to find an OB who would feel uncomfortable prescribing medications such as propanolol, metropolol and procardia during pregnancy.

It is also a matter of weighing the risks of not taking the medication with the risks involved in taking the medication. Often times you do not have much choice and anecdotal evidence demonstrates little to no risk. I was on propanolol while pregnant with DD and delivered a healthy girl with no IUGR at all.

Chat Icon Chat Icon



I agree that it is almost always a case of risk vs. benefit and that decision needs to be left up to the pt and her doctor. I just wanted to give the actual drug facts to the original poster, who may not have access to the medical references that I have. I was simply correcting the information given that labetolol was a category B drug.

Sure, there are many drugs that are used by plenty of pregnant women with no adverse events but to say that they are actually safer than they have been proven to be can give somebody a false sense of security. If a risk/benefit decision needs to be made, it needs to be made with all of the correct information possible - both anecdotal and proven. And for me, if there were a safer alternative available, I'd want to try that first.

Congratulations on your little girl. Chat Icon

Posted 12/9/08 5:41 PM
 
 

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